Ohno’s rule

It is striking that translocation and, in fact, other chromosomal restructuring rarely affect the genes on the sex X-chromosomes of mammals (termed Ohno’s rule (Ohno 1967).)Apparently, such restructuring, and especially translocation of genes between sex chromosomes and autosomes could interfere in the mechanism of determining sex based on the gene dose (number of copies of the given gene in the diploid cell) or in the mechanism of compensation of the gene dose (Kelley & Kuroda 1995).

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The classical Darwinian theory of evolution can explain the evolution of adaptive traits only in asexual organisms. The frozen plasticity theory is much more general: It can also explain the origin and evolution of adaptive traits in both asexual and sexual organisms Read more